… In 1979, Toth published a case series of 6 patients on sulfasalazine (SASP) for ulcerative …
While a complete review of neoplasms and male fertility is beyond the scope of our review, it is …

… male fertility by the same mechanism as this compound and were less toxic might be ideal
… Since the recognition of the side effects of sulphasalazine on male fertility, it has been …

… Moreover, male fertility was not affected, since the testosterone levels and … impairments in
sperm parameters that could compromise fertility. This study investigated the consequences of …

… The purpose of this review is to present an integrated overview of the existing literature
regarding male fertility as a marker for health (as assessed by genetics, health, exposures and …

… Whilst the focus of this review are women, concerns about fertility are also shared by … to
impact male fertility. However, specific IBD therapies do have an effect: sulfasalazine causes well-…

… In this review, we rated one point in each item of comparability, if age and other known risk
factors (such as sulfasalazine dose) were matched or adjusted in the analysis. The minimum …

… we aimed to review the … sulfasalazine had unchanged sulfasalazine in their caecum and
faeces, in contrast to the excreta of normal rats which did not contain unchanged sulfasalazine. …

… side effects of sulfasalazine, we suggest that this may be a rare side effect of sulfasalazine.
… This study was conducted in accordance with the Declaration of Helsinki, but ethical review …

… Several studies in the literature show that SAS treatment impairs male reproduction by 64
altering sperm parameters, causing transitory infertility in both humans [17–19] and rats [20– …

… This activity reviews the indications, contraindications, mode of action, adverse events, and
other key elements of sulfasalazine therapy in the clinical setting as relates to the essential …